I know this is an old topic but Chris Pratt was definitely put on the map by the MCU.
Now he was in 3 successful films before GotG -- Zero Dark Thirty, Moneyball, and The Lego Movie -- but he only got top billing in TLM but that only featured his voice. MCU made him a leading man.
They do NOT hear you
Him losing weight and playing Star Lord
COMPLETELY changed the trajectory of his career
You could argue Iron Man saved RDJ
Career AND life