People be very careful this virus is not done yet

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New Coronavirus Discovered in Chinese Bats Sparks Alarm​

Published Feb 21, 2025 at 8:06 AM EST




Anew bat coronavirus that has the capacity to spread to humans, similar to the one that caused the COVID-19 pandemic, has been discovered.
HKU5-CoV-2 was found by a Chinese research team led by virologist Shi Zhengli, known as "Batwoman" for her work on coronaviruses, especially at the Wuhan Institute, which has been at the center of the theory suggesting COVID-19 came from a lab leak—something Shi has denied.
Newsweek has contacted Shi for comment via email.

Why It Matters

Hundreds of coronaviruses exist but only a few can infect humans, including SARS, SARS-CoV-2 (the virus that causes COVID-19) and MERS (Middle East Respiratory Syndrome).

This new one (HKU5-CoV-2) uses the ACE2 receptor to infect organisms—SARS-CoV-2 also uses the ACE2 receptor for infection.

What is HKU5-CoV-2?

HKU5-CoV-2 is a coronavirus belonging to the merbecovirusgroup, which also includes the virus that causes MERS.
It has a higher potential to infect humans than other coronaviruses because of the way it binds to human ACE2, making it similar to SARS-CoV-2 and NL63 (a common cold virus).
Researchers came to this conclusion after using a technique called Cryo-EM, which uses a powerful microscope.

HKU5-CoV-2 was able to infect human cell cultures in the mini-human organ models the scientists used.
Read more Coronavirus
"Bat merbecoviruses, which are phylogenetically related to MERS-CoV, pose a high risk of spillover to humans, either through direct transmission or facilitated by intermediate hosts," the study says.
Shi Zheng-li

Virologist Shi Zhengli, left, works with a colleague at the Wuhan Institute of Virology in Wuhan, China, on February 23, 2017. AP

What To Know

The research, conducted by the Wuhan Institute of Virology, the Guangzhou Laboratory and the Guangzhou Academy of Sciences, was published in the scientific journal Cell.

The study says that the potential for the virus to spillover into humans "remains to be investigated."

What People Are Saying

The study says: "Structural and functional analyses indicate that HKU5-CoV-2 has a better adaptation to human ACE2 than lineage 1 HKU5-CoV."
The researchers found that: "Authentic HKU5-CoV-2 infected human ACE2-expressing cell lines and human respiratory and enteric organoids. This study reveals a distinct lineage of HKU5-CoVs in bats that efficiently use human ACE2 and underscores their potential zoonotic risk."

What Happens Next

Newsweek has contacted the United States Department of Health and Human Services, via email, for comment.
 

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Scientists Describe Rare Syndrome Following Covid Vaccinations​

In a small study, patients with the syndrome were more likely to experience reactivation of Epstein-Barr virus and high levels of a coronavirus protein.


A close-up view of a gloved hand grasping for Covid shots in a purple plastic case on a table in a clinic.

Like people with long Covid, some with post-vaccination syndrome showed reactivation of Epstein-Barr virus, which is linked to mononucleosis, multiple sclerosis and other conditions.Credit...Matthew Busch for The New York Times

By Apoorva Mandavilli
Published Feb. 19, 2025Updated Feb. 21, 2025, 10:08 a.m. ET
Leer en español

The Covid-19 vaccines were powerfully protective, preventing millions of deaths. But in a small number of people, the shots may have led to a constellation of side effects that includes fatigue, exercise intolerance, brain fog, tinnitus and dizziness, together referred to as “post-vaccination syndrome,” according to a small new study.

Some people with this syndrome appear to show distinct biological changes, the research found — among them differences in immune cells, reawakening of a dormant virus called Epstein-Barr, and the persistence of a coronavirus protein in their blood.

The study was posted online Wednesday and has not yet been published in a scientific journal. “I want to emphasize that this is still a work in progress,” said Akiko Iwasaki, an immunologist at Yale University who led the work.

“It’s not like this study determined what’s making people sick,” she said, “but it’s the first kind of glimpse at what may be going on within these people.”



Independent experts noted that the findings were not conclusive on their own. Yet the results, from a scientific team known for rigorous work, suggest that post-vaccination syndrome deserves further scrutiny, they said.

More on Covid-19​

“One of the most important things is that we get some attention to really shine a light on this and try to understand exactly what it is,” said John Wherry, director of the Institute for Immunology at the University of Pennsylvania. (Dr. Wherry has previously collaborated with Dr. Iwasaki’s team, but did not participate in this work.)

Thousands of people have said that Covid vaccines harmed them. But the United States’ fragmented health care system complicates detection of uncommon side effects and has provided little clarity on the range of symptoms people might have experienced after a Covid shot.

The patchwork has also made it difficult to compare and collate self-reported anecdotes. The new study is small, and the condition it is studying is “very heterogeneous,” said Dr. Gregory Poland, emeritus editor of the journal Vaccine and president of Atria Research Institute.

“Despite these limitations, they found interesting data that need further study,” he said. “Much larger studies of very carefully defined and phenotyped individuals need to take place.”


Between December 2022 and November 2023, Dr. Iwasaki and her team collected blood samples from 42 people with post-vaccination syndrome and 22 healthy people without it. People with the syndrome were generally in poorer health than the average American, the researchers found.

When they analyzed components of the immune system, those with post-vaccination syndrome had different proportions of some immune cells, compared with controls. It’s unclear what these differences might mean; the researchers did not link them to individual symptoms.
Because the symptoms reported by people with post-vaccination syndrome show considerable overlap with those of long Covid, the researchers also analyzed blood from 134 people with long Covid and 134 healthy controls.

Like people with long Covid, those with post-vaccination syndrome showed reactivation of Epstein-Barr virus, a virus that may lie dormant in the body and is linked to mononucleosis, multiple sclerosis and other conditions.

Some cases of long Covid are thought to result from the persistence of the spike protein of the coronavirus, resulting in a heightened state of inflammation in the body.

Dr. Iwasaki and her team found that people with post-vaccination syndrome had significantly higher plasma levels of the coronavirus spike protein than everyone else — including those with long Covid — from 26 to 709 days after receiving the vaccine.

Dr. Iwasaki said that mRNA itself, used in vaccines, was unlikely to be the source of the protein so long after the shots were administered. “Something else is allowing this sort of late-phase expression of spike protein, and we don’t really know what that is,” she said.

Dr. Wherry suggested caution in interpreting that result. For example, it’s possible that some of the protein may result from undetected coronavirus infections. “I would like to see more data on this topic,” he said.

Still, he added, the lack of clear answers makes it even more important to continue to explore the issue.

“One of the things that maybe scientists got trapped into a little bit during the pandemic is this perception that we should have all the answers, and if we can’t give it a definitive answer, then we shouldn’t be talking about it,” he said.

“I think that that’s a mistake,” he added. “We can’t say for certainty that this can’t happen.”
 

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Could you imagine how much worse the shortages would be this time around if we were in a trade war with China :smh:
"With millions of people dead in the first month and counting. Supreme Leader Emperor God Trump had no choice but to buy every robot that Tesla can build." Said Elon Musk today from his compound in Texas.

"We have to quickly replace all the workers lost, and those we will lose in the coming months while we let nature take it's course ... herd immunity will conquer the virus!" Said RFK Jr from an undisclosed bunker.
 
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